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UPSEM 817 tartrate

This compound is a highly selective and potent agonist for PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channels, with EC50 values of 0.3 nM and 0.5 nM, respectively. It effectively silences targeted neuronal activity in brain slices and induces robust rotational behavior in vivo in mouse models, making it a powerful tool for precise chemogenetic control of neuronal circuits.

Product Specifications

CAS Number

2341833-14-3

Smiles

O[C@H] ([C@@H] (O) C (O) =O) C (O) =O.CCCOc1cnc2cc3C4CC (CNC4) c3cc2n1 |THB:27:26:21:23.24.25,18:19:21:23.24.25|

Molecular Formula

C20H25N3O7

Molecular Weight

419.434

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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