Ac-FLTD-CMK
Ac-FLTD-CMK is a cell-permeable, irreversible inhibitor derived from abscisicin D that selectively targets inflammatory caspases. It potently inhibits caspase-1, -4, and -11 (with IC50 values in the nM to μM range) but not caspase-3, making it a useful tool for studying pyroptosis and inflammasome biology in cellular and animal models of inflammation.
Product Specifications
CAS Number
2376255-48-8
Product Name Alternative
Caspase-4, caspase-1, caspase-11, Ac FLTD CMK, AcFLTDCMK, Ac-FLTD-CMK
Field of Research
Cell Biology, Immunology & Inflammation, Protein Biochemistry
Purity
95.17% (May vary between batches)
Solubility
DMSO:150 mg/mL (263.6 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.8 mM)
Smiles
CC (C) C[C@H] (NC (=O) [C@H] (Cc1ccccc1) NC (C) =O) C (=O) N[C@@H] ([C@@H] (C) O) C (=O) N[C@@H] (CC (O) =O) C (=O) CCl
Molecular Formula
C26H37ClN4O8
Molecular Weight
569.05
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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