(R) -Bromoenol lactone (5 mg/ml solution in methyl acetate)
(R) -Bromoenol lactone is a potent and selective mechanism-based inhibitor of calcium-independent phospholipase A2γ (iPLA2γ), with an IC50 of ~0.6 μM, showing minimal activity against iPLA2β. This chiral compound is a valuable research tool for studying roles of iPLA2γ in lipid signaling, membrane dynamics, and associated in vitro and in vivo disease models.
Product Specifications
CAS Number
478288-90-3
Field of Research
Metabolism Research
Smiles
O=C1[C@@H] (C=2C3=C (C=CC2) C=CC=C3) CC/C (=C\Br) /O1
Molecular Formula
C16H13BrO2
Molecular Weight
317.18
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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