Combretastatin A-1
Combretastatin A-1 is a potent microtubule-depolymerizing agent with antitumor and anti-angiogenic properties. It inactivates AKT and suppresses the Wnt/β-catenin pathway, making it a valuable tool for studying hepatocellular carcinoma in both in vitro and in vivo models.
Product Specifications
CAS Number
109971-63-3
Product Name Alternative
Akt, Combretastatin A1, Combretastatin A-1, Combretastatin A 1, microtubule, Microtubule Associated, MicrotubuleAssociated
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
97.49% (May vary between batches)
Solubility
Ethanol:3 mg/mL (9.03 mM) ; DMSO:PBS (pH 7.2) (1:1) :0.5 mg/mL (1.5 mM) ; DMSO:80 mg/mL (240.71 mM) ; DMF:5 mg/mL (15.04 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.93 mM)
Smiles
COc1ccc (\C=C/c2cc (OC) c (OC) c (OC) c2) c (O) c1O
Molecular Formula
C18H20O6
Molecular Weight
332.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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