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Combretastatin A-1

Combretastatin A-1 is a potent microtubule-depolymerizing agent with antitumor and anti-angiogenic properties. It inactivates AKT and suppresses the Wnt/β-catenin pathway, making it a valuable tool for studying hepatocellular carcinoma in both in vitro and in vivo models.

Product Specifications

CAS Number

109971-63-3

Product Name Alternative

Akt, Combretastatin A1, Combretastatin A-1, Combretastatin A 1, microtubule, Microtubule Associated, MicrotubuleAssociated

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Purity

97.49% (May vary between batches)

Solubility

Ethanol:3 mg/mL (9.03 mM) ; DMSO:PBS (pH 7.2) (1:1) :0.5 mg/mL (1.5 mM) ; DMSO:80 mg/mL (240.71 mM) ; DMF:5 mg/mL (15.04 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.93 mM)

Smiles

COc1ccc (\C=C/c2cc (OC) c (OC) c (OC) c2) c (O) c1O

Molecular Formula

C18H20O6

Molecular Weight

332.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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