Heat Shock Protein Inhibitor II
Hsp inhibitor II is the bioactive benzylidene lactam form that suppresses inducible Hsp synthesis, including Hsp105, Hsp72, and Hsp40. It reduces tumor thermotolerance in vivo and inhibits thermotolerance development in vitro. Furthermore, it synergizes with amphotericin B to enhance antifungal efficacy against both susceptible and resistant A. fumigatus strains.
Product Specifications
CAS Number
1859-42-3
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (C=1C=C2C (=CC1) OCO2) =C3C (=O) NCC3
Molecular Formula
C12H11NO3
Molecular Weight
217.22
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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