What is the catalog number for BM-1244?

The catalog number for BM-1244 is orb1693363.

What sizes are available for BM-1244?

BM-1244 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does BM-1244 come in?

BM-1244 is available in 3 different pack sizes.

BM-1244 is currently made to order / not held in immediate stock. Contact us for lead time.

BM-1244

BM-1244 is a potent small molecule inhibitor of the anti-apoptotic proteins Bcl-xL (Ki = 134 nM) and Bcl-2 (Ki = 450 nM) . It effectively eliminates senescent cells in vitro, demonstrating an EC50 of 5 nM in senescent fibroblast assays, making it a useful research tool for studying apoptosis and senescence.

Product Specifications

CAS Number

1619923-32-8

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry

Smiles

CC (C) n1c (C) c (c (c1-c1ccc (Cl) cc1) -c1cc (F) cc (c1) N1CCN (CC1) c1ccc (NS (=O) (=O) c2ccc (N[C@H] (CCN3CCC (CC3) C (O) =O) CSc3ccccc3) c (c2) S (=O) (=O) C (F) (F) F) cc1) S (C) (=O) =O