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Pramlintide (acetate hydrate)

Pramlintide is a synthetic, non-amyloidogenic amylin analog with proline substitutions at positions 25, 28, and 29. It potently activates human amylin receptors (AMY1a/3a) and inhibits islet amyloid polypeptide fibrilization. This peptide is used in diabetes research to study metabolic regulation and amyloidosis in both in vitro and in vivo models.

Product Specifications

CAS Number

196078-30-5

Field of Research

Pharmacology & Drug Discovery

Smiles

CC[C@H] (C) [C@H] (NC (=O) [C@@H]1CCCN1C (=O) CNC (=O) [C@H] (Cc1ccccc1) NC (=O) [C@H] (CC (N) =O) NC (=O) [C@H] (CC (N) =O) NC (=O) [C@H] (CO) NC (=O) [C@H] (CO) NC (=O) [C@H] (Cc1c[nH]cn1) NC (=O) [C@@H] (NC (=O) [C@H] (CC (C) C) NC (=O) [C@H] (Cc1ccccc1) NC (=O) [C@H] (CC (N) =O) NC (=O) [C@H] (C) NC (=O) [C@H] (CC (C) C) NC (=O) [C@H] (CCCNC (N) =N) NC (=O) [C@H] (CC (N) =O) NC (=O) [C@@H] (NC (=O) [C@H] (C) NC (=O) [C@H] (CS) NC (=O) [C@@H] (NC (=O) [C@H] (C) NC (=O) [C@@H] (NC (=O) [C@H] (CC (N) =O) NC (=O) [C@H] (CS) NC (=O) [C@@H] (N) CCCCN) [C@@H] (C) O) [C@@H] (C) O) [C@@H] (C) O) C (C) C) C (=O) N[C@@H] (CC (C) C) C (=O) N1CCC[C@H]1C (=O) N1CCC[C@H]1C (=O) N[C@@H] ([C@@H] (C) O) C (=O) N[C@@H] (CC (N) =O) C (=O) N[C@@H] (C (C) C) C (=O) NCC (=O) N[C@@H] (CO) C (=O) N[C@@H] (CC (N) =O) C (=O) N[C@@H] ([C@@H] (C) O) C (=O) N[C@@H] (Cc1ccc (O) cc1) C (N) =O

Molecular Formula

C170H267N51O53S2

Molecular Weight

3937.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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