Pramlintide (acetate hydrate)
Pramlintide is a synthetic, non-amyloidogenic amylin analog with proline substitutions at positions 25, 28, and 29. It potently activates human amylin receptors (AMY1a/3a) and inhibits islet amyloid polypeptide fibrilization. This peptide is used in diabetes research to study metabolic regulation and amyloidosis in both in vitro and in vivo models.
Product Specifications
CAS Number
196078-30-5
Field of Research
Pharmacology & Drug Discovery
Smiles
CC[C@H] (C) [C@H] (NC (=O) [C@@H]1CCCN1C (=O) CNC (=O) [C@H] (Cc1ccccc1) NC (=O) [C@H] (CC (N) =O) NC (=O) [C@H] (CC (N) =O) NC (=O) [C@H] (CO) NC (=O) [C@H] (CO) NC (=O) [C@H] (Cc1c[nH]cn1) NC (=O) [C@@H] (NC (=O) [C@H] (CC (C) C) NC (=O) [C@H] (Cc1ccccc1) NC (=O) [C@H] (CC (N) =O) NC (=O) [C@H] (C) NC (=O) [C@H] (CC (C) C) NC (=O) [C@H] (CCCNC (N) =N) NC (=O) [C@H] (CC (N) =O) NC (=O) [C@@H] (NC (=O) [C@H] (C) NC (=O) [C@H] (CS) NC (=O) [C@@H] (NC (=O) [C@H] (C) NC (=O) [C@@H] (NC (=O) [C@H] (CC (N) =O) NC (=O) [C@H] (CS) NC (=O) [C@@H] (N) CCCCN) [C@@H] (C) O) [C@@H] (C) O) [C@@H] (C) O) C (C) C) C (=O) N[C@@H] (CC (C) C) C (=O) N1CCC[C@H]1C (=O) N1CCC[C@H]1C (=O) N[C@@H] ([C@@H] (C) O) C (=O) N[C@@H] (CC (N) =O) C (=O) N[C@@H] (C (C) C) C (=O) NCC (=O) N[C@@H] (CO) C (=O) N[C@@H] (CC (N) =O) C (=O) N[C@@H] ([C@@H] (C) O) C (=O) N[C@@H] (Cc1ccc (O) cc1) C (N) =O
Molecular Formula
C170H267N51O53S2
Molecular Weight
3937.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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