CXCR2-IN-2
CXCR2-IN-2 is a potent, selective, and brain-penetrant CXCR2 antagonist with oral bioavailability. It demonstrates high selectivity over CXCR1 and other chemokine receptors and effectively inhibits Gro-α-induced CD11b expression in human whole blood. This compound is a valuable tool for researching CXCR2's role in neuroinflammation, COPD, and cancer in both in vitro and in vivo models.
Product Specifications
CAS Number
1838123-21-9
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
S (=O) (=O) (C1=C (O) C (NC (N[C@H]2C (C) =CCC2) =O) =CC=C1Cl) [C@@]3 (C) CCOC3
Molecular Formula
C18H23ClN2O5S
Molecular Weight
414.9
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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