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PKUMDL-LC-101-D04

PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4), a key regulator of ferroptosis. It elevates GPX4 activity in cell-free and cellular assays, as demonstrated in wild-type MEFs, and protects cells from cholesterol peroxide-induced ferroptotic death. This compound is a valuable research tool for investigating ferroptosis in both in vitro and in vivo models.

Product Specifications

CAS Number

2143896-83-5

Product Name Alternative

PKUMDL-LC-101-D04, Gpx4, GPX4-Activator-1d4

Field of Research

Metabolism Research

Purity

98.71% (May vary between batches)

Solubility

DMSO:225 mg/mL (593.76 mM)

Smiles

Cl.NCCNS (=O) (=O) c1ccc (NC (=S) NC2CCCC2) cc1

Molecular Formula

C14H23ClN4O2S2

Molecular Weight

378.94

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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