PKUMDL-LC-101-D04
PKUMDL-LC-101-D04 is a potent allosteric activator of glutathione peroxidase 4 (GPX4), a key regulator of ferroptosis. It elevates GPX4 activity in cell-free and cellular assays, as demonstrated in wild-type MEFs, and protects cells from cholesterol peroxide-induced ferroptotic death. This compound is a valuable research tool for investigating ferroptosis in both in vitro and in vivo models.
Product Specifications
CAS Number
2143896-83-5
Product Name Alternative
PKUMDL-LC-101-D04, Gpx4, GPX4-Activator-1d4
Field of Research
Metabolism Research
Purity
98.71% (May vary between batches)
Solubility
DMSO:225 mg/mL (593.76 mM)
Smiles
Cl.NCCNS (=O) (=O) c1ccc (NC (=S) NC2CCCC2) cc1
Molecular Formula
C14H23ClN4O2S2
Molecular Weight
378.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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