Polygalaxanthone III
Polygalaxanthone III is a potent and selective inhibitor of CYP2E1, effectively blocking the 6-hydroxylation of chlorzoxazone in vitro. This makes it a valuable chemical probe for studying CYP2E1-mediated metabolism, drug interactions, and toxicity mechanisms in hepatic research models.
Product Specifications
CAS Number
162857-78-5
Product Name Alternative
Polygalaxanthone III, Inhibitor, inhibit, CYPs, Cytochrome P450
Field of Research
Metabolism Research
Purity
97.54% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.52 mM) ; DMSO:60 mg/mL (105.54 mM)
Smiles
COc1cc2c (cc1O) oc1cc (O) c ([C@@H]3O[C@H] (CO[C@@H]4OC[C@] (O) (CO) [C@H]4O) [C@@H] (O) [C@H] (O) [C@H]3O) c (O) c1c2=O
Molecular Formula
C25H28O15
Molecular Weight
568.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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