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GSK 591 dihydrochloride

This compound is a potent and selective PRMT5 inhibitor with an IC50 of 4 nM, demonstrating anti-proliferative activity in mantle cell lymphoma models. It is a valuable chemical probe for investigating PRMT5 biology in cancer research, including studies of splicing regulation and cellular differentiation.

Product Specifications

CAS Number

2320953-89-5

Field of Research

Epigenetics & Chromatin

Smiles

Cl.Cl.O[C@@H] (CNC (=O) c1ccnc (NC2CCC2) c1) CN1CCc2ccccc2C1

Molecular Formula

C22H30Cl2N4O2

Molecular Weight

453.41

Storage Conditions

-20°C

Notes

For research use only.

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