CXCR3 Antagonist 6c
CXCR3 antagonist 6c is a potent and selective small molecule inhibitor of the CXCR3 receptor, blocking CXCL11-induced calcium flux (IC50=0.06 μM) and human T-cell migration (IC50≈100 nM) . Its selectivity and activity make it a valuable research tool for studying CXCR3's role in T-cell trafficking and associated diseases like autoimmunity and inflammation in both cellular and animal models.
Product Specifications
CAS Number
870998-13-3
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology
Smiles
N (C (=O) C1=CC (Cl) =CC=C1) C2=C (C=CC (C (NCCC3=C (Cl) C=C (Cl) C=C3) =O) =C2) N4CCN (C (NCC) =O) CCC4
Molecular Formula
C30H32Cl3N5O3
Molecular Weight
616.97
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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