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MRT 67307 dihydrochloride

MRT67307 dihydrochloride is a potent dual inhibitor of IKKε (IC50=160 nM) and TBK1 (IC50=19 nM), and also inhibits ULK1/2, thereby blocking autophagy. This compound is a valuable research tool for studying innate immunity, autophagy signaling, and their roles in cancer and inflammatory diseases in cellular models.

Product Specifications

CAS Number

1781882-89-0

Product Name Alternative

MRT 67307, MRT 67307 Dihydrochloride, MRT 67307 dihydrochloride, MRT67307, MRT-67307, MRT67307 Dihydrochloride, MRT-67307 Dihydrochloride, Salt-inducible Kinase (SIK)

Field of Research

Cell Biology, Signal Transduction

Purity

98.43% (May vary between batches)

Solubility

DMSO:82.8 mg/mL (154.04 mM)

Smiles

O=C (C1CCC1) NCCCNC2=NC (NC3=CC=CC (CN4CCOCC4) =C3) =NC=C2C5CC5.Cl.Cl

Molecular Formula

C26H38Cl2N6O2

Molecular Weight

537.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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