MRT 67307 dihydrochloride
MRT67307 dihydrochloride is a potent dual inhibitor of IKKε (IC50=160 nM) and TBK1 (IC50=19 nM), and also inhibits ULK1/2, thereby blocking autophagy. This compound is a valuable research tool for studying innate immunity, autophagy signaling, and their roles in cancer and inflammatory diseases in cellular models.
Product Specifications
CAS Number
1781882-89-0
Product Name Alternative
MRT 67307, MRT 67307 Dihydrochloride, MRT 67307 dihydrochloride, MRT67307, MRT-67307, MRT67307 Dihydrochloride, MRT-67307 Dihydrochloride, Salt-inducible Kinase (SIK)
Field of Research
Cell Biology, Signal Transduction
Purity
98.43% (May vary between batches)
Solubility
DMSO:82.8 mg/mL (154.04 mM)
Smiles
O=C (C1CCC1) NCCCNC2=NC (NC3=CC=CC (CN4CCOCC4) =C3) =NC=C2C5CC5.Cl.Cl
Molecular Formula
C26H38Cl2N6O2
Molecular Weight
537.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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