7β,27-dihydroxy Cholesterol
7β,27-dihydroxycholesterol is a selective endogenous agonist for RORγ and RORγt, activating receptor signaling and enhancing IL-17A production in both human Th17 cells and mouse γδ T cells in vitro and in vivo. This oxysterol is a valuable research tool for studying Th17 biology, autoimmunity, and RORγt-related transcriptional regulation.
Product Specifications
CAS Number
240129-43-5
Field of Research
Metabolism Research
Smiles
C[C@@H] (CO) CCC[C@@H] (C) [C@H]1CC[C@H]2[C@@H]3[C@@H] (O) C=C4C[C@@H] (O) CC[C@]4 (C) [C@H]3CC[C@]12C
Molecular Formula
C27H46O3
Molecular Weight
418.65
Storage Conditions
-20°C
Notes
For research use only.
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