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MCC950

MCC950 (CP-456773) is a potent and selective NLRP3 inflammasome inhibitor with an IC50 in the low nanomolar range. It is widely used in research models of inflammatory diseases, autoimmunity, and neurological disorders, demonstrating efficacy in both in vitro cellular assays and in vivo animal studies.

Product Specifications

CAS Number

210826-40-7

Product Name Alternative

CRID 3, CRID3, CRID-3, CP456773, CP-456773, CP 456773, MCC-950, MCC 950, MCC950, Inhibitor, inhibit, NOD-like Receptor (NLR), NLRP3

Field of Research

Immunology & Inflammation, Signal Transduction

Purity

97.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.16 mM) ; DMSO:83.33 mg/mL (206.02 mM)

Smiles

CC (C) (O) c1coc (c1) S (=O) (=O) NC (=O) Nc1c2CCCc2cc2CCCc12

Molecular Formula

C20H24N2O5S

Molecular Weight

404.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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