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(Z) -4EGI-1

(Z) -4EGI-1 is a cell-permeable inhibitor that disrupts the eIF4E/eIF4G interaction, thereby suppressing cap-dependent translation initiation with an IC50 of 43.5 μM. This compound exhibits anticancer properties and is used in research to study oncogenesis and protein synthesis inhibition in both cellular and animal models.

Product Specifications

CAS Number

901787-88-0

Field of Research

Cell Biology

Smiles

N (/N=C (/CC1=C (N (=O) =O) C=CC=C1) \C (O) =O) C2=NC (=CS2) C3=CC (Cl) =C (Cl) C=C3

Molecular Formula

C18H12Cl2N4O4S

Molecular Weight

451.28

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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