(Z) -4EGI-1
(Z) -4EGI-1 is a cell-permeable inhibitor that disrupts the eIF4E/eIF4G interaction, thereby suppressing cap-dependent translation initiation with an IC50 of 43.5 μM. This compound exhibits anticancer properties and is used in research to study oncogenesis and protein synthesis inhibition in both cellular and animal models.
Product Specifications
CAS Number
901787-88-0
Field of Research
Cell Biology
Smiles
N (/N=C (/CC1=C (N (=O) =O) C=CC=C1) \C (O) =O) C2=NC (=CS2) C3=CC (Cl) =C (Cl) C=C3
Molecular Formula
C18H12Cl2N4O4S
Molecular Weight
451.28
Storage Conditions
-20°C
Notes
For research use only.
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