YNT-185 dihydrochloride
This small molecule is a potent and selective OX2 receptor agonist (hOX2 EC50 = 28 nM; >100-fold selective over hOX1) . It depolarizes histaminergic neurons in vitro and promotes wakefulness in wild-type mice while suppressing cataplexy in orexin-deficient models, making it a valuable tool for studying sleep/wake regulation and narcolepsy.
Product Specifications
CAS Number
1804978-82-2
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
Cl.Cl.COc1ccc (cc1S (=O) (=O) Nc1cccc (NCCNC (=O) c2ccccc2N (C) C) c1) -c1cccc (c1) C (=O) N (C) C
Molecular Formula
C33H39Cl2N5O5S
Molecular Weight
688.67
Storage Conditions
-20°C
Notes
For research use only.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
338561-01 50 µL
Tumor necrosis factor Receptor superfamily member 27 (EDA2R)
Sign In for Pricing
View Details 338561-02 100 µL
Tumor necrosis factor Receptor superfamily member 27 (EDA2R)
Sign In for Pricing
View Details 