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Resolvin D1 methyl ester

Resolvin D1 methyl ester is a lipophilic prodrug form of the specialized pro-resolving mediator RvD1, which is enzymatically derived from docosahexaenoic acid. Intracellular esterases cleave the ester to release the active free acid, which potently inhibits neutrophil transendothelial migration (EC50 ~30 nM) to resolve inflammation. This compound is a key research tool for studying inflammation resolution mechanisms in both cellular and animal models of disease.

Product Specifications

CAS Number

937738-63-1

Smiles

[C@@H] ([C@@H] (/C=C/C=C/C=C\C=C\[C@H] (C/C=C\CC) O) O) (C/C=C\CCC (OC) =O) O

Molecular Formula

C23H34O5

Molecular Weight

390.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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