MMP-9/MMP-13 Inhibitor I
This compound is a potent and selective dual inhibitor of MMP-9 and MMP-13, exhibiting IC50 values of 0.9 nM for each enzyme with over 20-fold selectivity against other MMPs. It is a valuable research tool for studying extracellular matrix remodeling in pathologies such as osteoarthritis, cancer invasion, and atherosclerosis in both cellular and animal models.
Product Specifications
CAS Number
204140-01-2
Field of Research
Cancer Biology; Musculoskeletal & Connective Tissue Research; Pharmacology & Drug Discovery, Protein Biochemistry
Smiles
O=C (C=1C=CC (=CC1) C=2C=CC=CC2) N3CCN (C (C (=O) NO) C3) S (=O) (=O) C4=CC=C (OC) C=C4
Molecular Formula
C25H25N3O6S
Molecular Weight
495.55
Storage Conditions
-20°C
Notes
For research use only.
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