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14,15-dehydro Leukotriene B4

14,15-dehydro LTB4 is a potent and selective BLT1 receptor antagonist (Ki = 27 nM) derived from arachidonic acid metabolism. It is a valuable research tool for studying leukotriene B4 signaling, used in vitro to inhibit LTB4-induced functions like lysozyme release (IC50 = 1 μM) and in vivo to investigate inflammatory pathways.

Product Specifications

CAS Number

114616-11-4

Field of Research

Pharmacology & Drug Discovery

Smiles

C (=C\C=C\C=C\[C@@H] (CC#CCCCCC) O) \[C@H] (CCCC (O) =O) O

Molecular Formula

C20H30O4

Molecular Weight

334.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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