RN-9893 (hydrochloride)
RN-9893 is a selective TRPV4 antagonist with IC50 values in the sub-micromolar range for both human and rat receptors. It effectively inhibits TRPV4 activity induced by chemical agonists or hypotonic stress in vitro, and its selectivity over other TRPV channels makes it a valuable research tool for studying TRPV4's role in pain, inflammation, and osmosensation.
Product Specifications
CAS Number
2109450-40-8
Field of Research
Pharmacology & Drug Discovery
Smiles
Cl.O=C (NC1=CC=C (C=C1) S (=O) (=O) N2CCN (CC2) C (C) C) C3=CC=C (C=C3N (=O) =O) C (F) (F) F
Molecular Formula
C21H24ClF3N4O5S
Molecular Weight
536.95
Storage Conditions
-20°C
Notes
For research use only.
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