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RN-9893 (hydrochloride)

RN-9893 is a selective TRPV4 antagonist with IC50 values in the sub-micromolar range for both human and rat receptors. It effectively inhibits TRPV4 activity induced by chemical agonists or hypotonic stress in vitro, and its selectivity over other TRPV channels makes it a valuable research tool for studying TRPV4's role in pain, inflammation, and osmosensation.

Product Specifications

CAS Number

2109450-40-8

Field of Research

Pharmacology & Drug Discovery

Smiles

Cl.O=C (NC1=CC=C (C=C1) S (=O) (=O) N2CCN (CC2) C (C) C) C3=CC=C (C=C3N (=O) =O) C (F) (F) F

Molecular Formula

C21H24ClF3N4O5S

Molecular Weight

536.95

Storage Conditions

-20°C

Notes

For research use only.

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