Zetomipzomib
KZR-616 is a first-in-class, selective immunoproteasome inhibitor targeting the LMP7 and LMP2 subunits. It shows potential for researching autoimmune diseases, with studies demonstrating its activity in both in vitro enzymatic assays and in vivo models of lupus and rheumatoid arthritis.
Product Specifications
CAS Number
1629677-75-3
Field of Research
Protein Biochemistry
Smiles
C ([C@H] (CC=1CCCC1) NC ([C@H] ([C@H] (O) C2=CC=C (OC) C=C2) NC ([C@@H] (NC (CN3CCOCC3) =O) C) =O) =O) (=O) [C@@]4 (C) CO4
Molecular Formula
C30H42N4O8
Molecular Weight
586.68
Storage Conditions
-20°C
Notes
For research use only.
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