FIIN-1
FIIN-1 is a potent, selective, and irreversible inhibitor of FGFR isoforms, demonstrating low nanomolar Kd and IC50 values for FGFR1-3. It is a valuable chemical probe for studying FGFR signaling in cancer research, applicable in both cellular and biochemical assays.
Product Specifications
CAS Number
1256152-35-8
Product Name Alternative
FIIN 1, FIIN1, FIIN-1, FGFR, FGFR irreversible inhibitor-1
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.30% (May vary between batches)
Solubility
DMSO:45 mg/mL (68.53 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.05 mM)
Smiles
C (N1C=2C (CN (C1=O) C3=C (Cl) C (OC) =CC (OC) =C3Cl) =CN=C (NCCCCN (CC) CC) N2) C4=CC (NC (C=C) =O) =CC=C4
Molecular Formula
C32H39Cl2N7O4
Molecular Weight
656.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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