SR 12460
SR 12460 is a small molecule that acts as an NBD mimetic, disrupting the IKKβ/NEMO interaction to inhibit NF-κB activation triggered by TNF-α or LPS. It has demonstrated efficacy in cellular assays and reduces acute pulmonary inflammation in mouse models, making it a useful research tool for studying inflammatory signaling pathways.
Product Specifications
CAS Number
2055101-66-9
Smiles
O=C (NC1=NC=C (Cl) C=C1) CNCCC=2C=C (F) C=C (F) C2
Molecular Formula
C15H14ClF2N3O
Molecular Weight
325.74
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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