Antimycin A4
Antimycin A4, the most polar congener in the antimycin complex, is an inhibitor of ATP-citrate lyase (Ki=64.8 μM) and mitochondrial complex III. This inhibition blocks electron transport, depletes ATP, and increases superoxide production, making it a key research tool for studying respiration, apoptosis via Bcl-2/Bcl-xL inhibition, and oxidative stress in vitro.
Product Specifications
CAS Number
27220-59-3
Smiles
CCCC[C@@H]1[C@@H] (OC (=O) CCC) [C@H] (C) OC (=O) [C@@H] (NC (=O) c2cccc (NC=O) c2O) [C@@H] (C) OC1=O
Molecular Formula
C25H34N2O9
Molecular Weight
506.552
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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