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DDRI-18

DDRI-18 is a novel small molecule that disrupts the DNA damage response by inhibiting non-homologous end joining (NHEJ) . It acts as a chemosensitizer, enhancing the cytotoxicity of DNA-damaging agents in cancer research, with demonstrated efficacy in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

4402-18-0

Product Name Alternative

DDRI18, DDRI-18, DDRI 18, DNA/RNA Synthesis, DNA Synthesis, DNASynthesis, RNASynthesis, RNA Synthesis

Field of Research

Cell Biology, Molecular Biology

Solubility

DMSO:20 mg/mL (48.02 mM)

Smiles

NC=1C=C (C=2NC=3C (N2) =CC=C (C3) C=4C=C5C (=CC4) N=C (N5) C6=CC (N) =CC=C6) C=CC1

Molecular Formula

C26H20N6

Molecular Weight

416.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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