DDRI-18
DDRI-18 is a novel small molecule that disrupts the DNA damage response by inhibiting non-homologous end joining (NHEJ) . It acts as a chemosensitizer, enhancing the cytotoxicity of DNA-damaging agents in cancer research, with demonstrated efficacy in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
4402-18-0
Product Name Alternative
DDRI18, DDRI-18, DDRI 18, DNA/RNA Synthesis, DNA Synthesis, DNASynthesis, RNASynthesis, RNA Synthesis
Field of Research
Cell Biology, Molecular Biology
Solubility
DMSO:20 mg/mL (48.02 mM)
Smiles
NC=1C=C (C=2NC=3C (N2) =CC=C (C3) C=4C=C5C (=CC4) N=C (N5) C6=CC (N) =CC=C6) C=CC1
Molecular Formula
C26H20N6
Molecular Weight
416.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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