SCH-336
SCH-336 is a potent, selective, and orally active CB2 receptor agonist (Ki 1.8 nM) with 100-fold selectivity over CB1. It demonstrates functional activity by inhibiting GTPγS binding, CB2-mediated cell migration in vitro, and attenuating leukocyte migration and pulmonary eosinophilia in murine models of delayed hypersensitivity and allergy.
Product Specifications
CAS Number
447459-51-0
Product Name Alternative
CB2, CannabinoidReceptor, Cannabinoid Receptor, SCH-225336, SCH 336, SCH336, SCH-336
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
95.01% (May vary between batches)
Solubility
DMSO:90 mg/mL (166.78 mM)
Smiles
S (=O) (=O) (C1=C (S (=O) (=O) C2=CC=C (OC) C=C2) C=C (OC) C=C1) C3=CC=C ([C@@H] (NS (C) (=O) =O) C) C=C3
Molecular Formula
C23H25NO8S3
Molecular Weight
539.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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