GS-9191
GS-9191 is a prodrug of the nucleoside analog PMEG, which acts as a potent inhibitor of DNA polymerases alpha and beta. Its active triphosphate form exhibits antiproliferative effects, demonstrating dose-dependent reduction of papilloma size in vivo, supporting its research application for HPV-related lesion studies.
Product Specifications
CAS Number
859209-84-0
Product Name Alternative
DNASynthesis, DNA Synthesis, DNA polymerase beta, DNA polymerase α, GS9191, GS-9191, GS 9191, RNA Synthesis, RNASynthesis
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology
Purity
97.83% (May vary between batches)
Solubility
DMSO:7.35 mg/mL (10 mM)
Smiles
C (COCP (N[C@@H] (CC1=CC=CC=C1) C (OCC (C) C) =O) (N[C@@H] (CC2=CC=CC=C2) C (OCC (C) C) =O) =O) N3C=4C (=C (NC5CC5) N=C (N) N4) N=C3
Molecular Formula
C37H51N8O6P
Molecular Weight
734.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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