Phox-I1
Phox-I1 is a selective small molecule inhibitor of the NADPH oxidase 2 (NOX2) complex. It functions by disrupting the critical protein-protein interaction between the p67phox subunit and Rac GTPase, thereby blocking superoxide production. This inhibitor is a valuable research tool for studying NOX2's role in oxidative stress, inflammation, and related pathologies in both cellular and animal models.
Product Specifications
CAS Number
1388151-90-3
Field of Research
Immunology & Inflammation, Metabolism Research, Signal Transduction
Smiles
COc1ccc2OC (N3N=C (CC3c2c1) c1ccccc1) c1cccc (c1) [N+] ([O-]) =O
Molecular Formula
C23H19N3O4
Molecular Weight
401.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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