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GSK951A

GSK951A is a small molecule inhibitor targeting the EchA6 enzyme and fatty acid synthase II (FAS-II) in mycobacteria. It potently blocks mycolic acid biosynthesis and suppresses methoxy-, keto-, and alpha-mycolates (MAMEs) in M. bovis BCG, while leaving FAMEs largely intact, making it a valuable tool for studying mycobacterial cell wall synthesis in vitro.

Product Specifications

CAS Number

1403602-33-4

Field of Research

Infectious Disease & Virology

Smiles

C (NCC=1C=C2C (=CC1) OCO2) (=O) C3=C4N ([C@H] (C (F) (F) F) C[C@@H] (N4) C5=CC=C (CC) C=C5) N=C3

Molecular Formula

C24H23F3N4O3

Molecular Weight

472.46

Storage Conditions

-20°C

Notes

For research use only.

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