MLN-3897
MLN-3897 is a potent, orally bioavailable CCR1 antagonist with a Ki of 2.3 nM. It blocks MIP-1α binding, inhibits downstream Akt signaling, and suppresses multiple myeloma cell survival and proliferation in vitro, making it a useful research tool for studying inflammation and oncology pathways.
Product Specifications
CAS Number
1010731-97-1
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
98.62% (May vary between batches)
Smiles
C (CCN1CC (C) (C) [C@] (O) (CC1) C2=CC=C (Cl) C=C2) =C3C=4C (OCC=5C3=CC=CN5) =CC=C (C (O) =O) C4
Molecular Formula
C30H31ClN2O4
Molecular Weight
519.03
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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