Cgp 43182
CGP 43182 is a potent and selective inhibitor of Group IIA sPLA2 enzyme activity. It is utilized in research to investigate inflammatory pathways, as it blocks the NF-κB-mediated synergistic upregulation of pro-inflammatory genes induced by cytokines in vitro. This compound serves as a key tool for studying sPLA2's role in models of inflammation.
Product Specifications
CAS Number
150379-37-6
Smiles
O=C1OC2 (OC (O) =C1C (NC3=C (Cl) C (Cl) =CC=C3) =O) CCCCC2
Molecular Formula
C16H15Cl2NO5
Molecular Weight
372.2
Storage Conditions
-20°C
Notes
For research use only.
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