LANA-DNA-IN-1

LANA-DNA-IN-1 is a potent LANA-DNA inhibitor. LANA-DNA-IN-1 has inhibition activity for LBS2, LBS1 and LBS3 with IC50 values of 8 μM, 9μM and 8μM. LANA-DNA-IN-1shows against wild-type LANA with IC50 value of 53 μM. LANA-DNA-IN-1 can be used for the research of infection[1].

Product Specifications

CAS Number

[2512847-06-0]

UNSPSC

12352005

Target

HSV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/lana-dna-in-1.html

Purity

99.68

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=CC2=C(C=NC=C2C=C1)N3C=C(N=N3)C4=CC=C(C=C4)C(O)=O

Molecular Formula

C19H14N4O2

Molecular Weight

330.34

References & Citations

[1]Philine Kirsch, et al. Hit-to-lead optimization of a latency-associated nuclear antigen inhibitor against Kaposi's sarcoma-associated herpesvirus infections. Eur J Med Chem. 2020 Sep 15;202:112525