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SH-5

SH-5 is a potent AKT inhibitor that induces apoptosis and suppresses cancer cell invasion. It achieves this by blocking IκBα kinase activation, which downregulates key anti-apoptotic, proliferative, and metastatic proteins. This mechanism supports its use in vitro and in vivo for oncology research, particularly in studying PI3K/AKT pathway dysregulation.

Product Specifications

CAS Number

701976-54-7

Field of Research

Cell Biology, Signal Transduction

Smiles

O (P (OC[C@@H] (COCCCCCCCCCCCCCCCCCC) OC) (=O) O) [C@@H]1[C@H] (OC) C[C@@H] (O) [C@H] (O) [C@H]1O

Molecular Formula

C29H59O10P

Molecular Weight

598.75

Storage Conditions

-20°C

Notes

For research use only.

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