Valiglurax
Valiglurax (VU2957) is a potent, selective, and brain-penetrant positive allosteric modulator of the mGlu4 receptor with oral bioavailability. It demonstrates favorable drug metabolism and pharmacokinetic properties in preclinical studies. This compound is a development candidate for Parkinson's disease, supported by its efficacy in models of motor function.
Product Specifications
CAS Number
1976050-09-5
Product Name Alternative
MGlu4, Valiglurax, VU 2957, VU 0652957, VU2957, VU-2957, VU0652957, VU-0652957
Field of Research
Neuroscience
Purity
97.38% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (12.15 mM) ; DMSO:112.5 mg/mL (341.65 mM)
Smiles
C (F) (F) (F) C=1C2=C (C=C (NC=3C=4C (NN3) =NC=CC4) C=C2) C=CN1
Molecular Formula
C16H10F3N5
Molecular Weight
329.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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