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Valiglurax

Valiglurax (VU2957) is a potent, selective, and brain-penetrant positive allosteric modulator of the mGlu4 receptor with oral bioavailability. It demonstrates favorable drug metabolism and pharmacokinetic properties in preclinical studies. This compound is a development candidate for Parkinson's disease, supported by its efficacy in models of motor function.

Product Specifications

CAS Number

1976050-09-5

Product Name Alternative

MGlu4, Valiglurax, VU 2957, VU 0652957, VU2957, VU-2957, VU0652957, VU-0652957

Field of Research

Neuroscience

Purity

97.38% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (12.15 mM) ; DMSO:112.5 mg/mL (341.65 mM)

Smiles

C (F) (F) (F) C=1C2=C (C=C (NC=3C=4C (NN3) =NC=CC4) C=C2) C=CN1

Molecular Formula

C16H10F3N5

Molecular Weight

329.28

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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