I-SAP
I-SAP is a potent and high-affinity thromboxane prostanoid (TP) receptor antagonist. It induces platelet shape change without aggregation (EC50 9.7 nM) and exhibits sub-nanomolar binding affinity to human platelets across physiologic pH. This compound is a valuable tool for investigating TP receptor function in cardiovascular and thrombotic research using in vitro platelet assays.
Product Specifications
CAS Number
133538-58-6
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
C (/C=C\CCCC (O) =O) [C@H]1[C@]2 (C (C) (C) [C@] (C2) (C[C@@H]1NS (=O) (=O) C3=CC=C (I) C=C3) [H]) [H]
Molecular Formula
C22H30INO4S
Molecular Weight
531.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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