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RNF5 inhibitor inh-02

Inh-02 is a selective RNF5/RMA1 ubiquitin ligase inhibitor used in cystic fibrosis research. It promotes functional rescue of F508del-CFTR in cellular models and modulates substrates like ATG4B and paxillin, providing a tool for studying CFTR trafficking and proteostasis mechanisms.

Product Specifications

CAS Number

324579-65-9

Product Name Alternative

RNF5 inhibitor inh 02, RNF5 inhibitor inh02, RNF-5 inhibitor inh-02, RNF5 inhibitor inh-02

Field of Research

Cell Biology, Pharmacology & Drug Discovery; Cell Biology, Protein Biochemistry

Purity

99.23% (May vary between batches)

Solubility

DMSO:80 mg/mL (208.06 mM)

Smiles

N=1SC (=NC (=NC=2C=CC=CC2) C=3C=CC=CC3) N (C1C) CC=4C=CC=CC4

Molecular Formula

C23H20N4S

Molecular Weight

384.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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