KR-32568
KR-32568 is a potent and selective NHE-1 inhibitor (IC50: 230 nM) with demonstrated cardioprotective properties. In vitro, it restored cardiac function in ischemic rat hearts, while in vivo administration significantly reduced myocardial infarct size in rat models of ischemia-reperfusion injury.
Product Specifications
CAS Number
852146-73-7
Product Name Alternative
Na+/H+-exchanger (NHE), KR 32568, KR32568, KR-32568, SodiumChannel, Sodium Channel
Field of Research
Pharmacology & Drug Discovery
Purity
99.89% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (12.63 mM) ; DMSO:90 mg/mL (344.5 mM)
Smiles
CC1=C (C=2OC (C (NC (=N) N) =O) =CC2) C=C (F) C=C1
Molecular Formula
C13H12FN3O2
Molecular Weight
261.25
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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