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KR-32568

KR-32568 is a potent and selective NHE-1 inhibitor (IC50: 230 nM) with demonstrated cardioprotective properties. In vitro, it restored cardiac function in ischemic rat hearts, while in vivo administration significantly reduced myocardial infarct size in rat models of ischemia-reperfusion injury.

Product Specifications

CAS Number

852146-73-7

Product Name Alternative

Na+/H+-exchanger (NHE), KR 32568, KR32568, KR-32568, SodiumChannel, Sodium Channel

Field of Research

Pharmacology & Drug Discovery

Purity

99.89% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (12.63 mM) ; DMSO:90 mg/mL (344.5 mM)

Smiles

CC1=C (C=2OC (C (NC (=N) N) =O) =CC2) C=C (F) C=C1

Molecular Formula

C13H12FN3O2

Molecular Weight

261.25

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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