Sorafenib N-oxide
Sorafenib N-oxide, an active metabolite of sorafenib, is a potent and selective inhibitor of FLT3-ITD mutant kinase, showing efficacy in cellular models of acute myeloid leukemia (AML) . It also acts as a linear-mixed inhibitor of CYP3A4. This compound is a valuable research tool for studying targeted therapies in FLT3-ITD-driven AML and investigating drug-drug interaction potentials.
Product Specifications
CAS Number
583840-03-3
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
CNC (=O) c1cc (Oc2ccc (NC (=O) Nc3ccc (Cl) c (c3) C (F) (F) F) cc2) ccn1=O
Molecular Formula
C21H16ClF3N4O4
Molecular Weight
480.83
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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