HS271
HS271 is a potent and selective oral IRAK4 inhibitor with an IC50 of 7.2 μM. It demonstrates robust activity in both biochemical and cellular assays, alongside favorable pharmacokinetics, supporting its use in researching IRAK4-mediated pathways in autoimmune and inflammatory diseases.
Product Specifications
CAS Number
2410393-15-4
Product Name Alternative
IRAK4, HS271, HS-271, HS 271
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
98.12% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.58 mM) ; DMSO:90 mg/mL (206.69 mM)
Smiles
CN (C) CCn1cc2cc (NC (=O) c3cccc (n3) C (F) (F) F) c (cc2n1) C (C) (C) O
Molecular Formula
C21H24F3N5O2
Molecular Weight
435.44
Storage Conditions
-20°C
Notes
For research use only.
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