Clitocine
Clitocine is a mushroom-derived adenosine analog that acts as a potent transcriptional readthrough agent, suppressing nonsense mutations and elevating p53 in relevant mutant cells. It also promotes TRAIL-induced apoptosis in colon cancer models through Mcl-1 degradation. NSC 81464 is a yohimbine-type alkaloid isolated from Rauwolfia vomitoria.
Product Specifications
CAS Number
105798-74-1
Product Name Alternative
Clitocine, Apoptosis, Mcl-1
Field of Research
Cell Biology
Purity
≥95.0% (May vary between batches)
Solubility
DMSO:80 mg/mL (278.52 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (11.49 mM)
Smiles
Nc1ncnc (N[C@@H]2O[C@H] (CO) [C@@H] (O) [C@H]2O) c1[N+] ([O-]) =O
Molecular Formula
C9H13N5O6
Molecular Weight
287.23
Storage Conditions
-20°C
Notes
For research use only.
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